Three Major Pathways to Choose the Best Treatment
Each pathway targets a distinct mechanism in dry eye disease, enabling clinicians to select the most appropriate therapeutic strategy.
Pathway 1
Increase or Restore Meibomian Gland Secretory Function
Thermotherapies
IPL
QMR
Jett
LLLT
Orbicular Stimulation
Pathway 2
Increase or Restore Lacrimal Gland Secretory Function
Outflow Modulation
Lacrimal Outflow Modulation Therapies
Plugs
Intracanalicular Gels
Thermal Occlusion
Surgical Occlusion
Gland Stimulation
Krause & Wolfring stimulation by Jett
Secretagogues (Tear Stimulants)
Cholinergic Agonists
Pilocarpine
Cevimeline
Nasal Neurostimulation Agents
Varenicline nasal
Tyrvaya
Pathway 3
Enhance or Restore Goblet Cell-Mediated Mucin Secretion
Mucin Secretagogues / Goblet Cell Modulators
Diquafosol
Rebamipide
Lipid Layer Modulators
Omega-3 Supplements / Lipid Nutraceuticals
Lipid-based Artificial Tears
Supplementation
Tear Substitutes (Artificial Tears / Lubricants)
Goblet Cell stimulation by Jett